Back to Search Start Over

Multicentre study revealed significant gaps between evidence-based recommendations for using corticosteroids for croup and clinical practice.

Authors :
Pierantoni, Luca
Stera, Giacomo
Andreozzi, Laura
Pellegrino, Francesco
Dondi, Arianna
Fabi, Marianna
Corsini, Ilaria
Ghizzi, Chiara
Lanari, Marcello
Source :
Acta Paediatrica; Oct2022, Vol. 111 Issue 10, p2010-2016, 7p
Publication Year :
2022

Abstract

<bold>Aim: </bold>Adherence to croup management recommendations has been poorly investigated. This study aimed to describe the treatment patterns in two paediatric emergency departments and analyse the adherence to recommendations.<bold>Methods: </bold>We conducted a retrospective chart review of children diagnosed with croup in two Italian paediatric emergency departments in 2017. Data on clinical presentation, corticosteroid administration and home therapy were collected. Length of stay, hospitalisation and re-access rates were compared among different corticosteroid treatment groups.<bold>Results: </bold>We enrolled 632 patients (61.1% males) with a mean age of 42.8 ± 55.1 months. Corticosteroids were administered to 403 (63.8%) children in the emergency departments. Dexamethasone was administered to 1 (0.4%) patient. Inhaled and oral corticosteroids were given to 342 (54.1%) and 226 (35.8%) patients, respectively. Home therapy was prescribed for 603 (95.4%) patients, either with inhaled (86.2%) and/or oral (43.8%) corticosteroids. The re-access rate was 2.8%. The actual pharmaceutical costs were an estimated 10 times higher than they would have been if the recommendations had been followed.<bold>Conclusion: </bold>A significant gap between the evidence and clinical practice for croup treatment was observed. Improving adherence to the recommendations could lead to clinical and economic benefits. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
08035253
Volume :
111
Issue :
10
Database :
Complementary Index
Journal :
Acta Paediatrica
Publication Type :
Academic Journal
Accession number :
159025245
Full Text :
https://doi.org/10.1111/apa.16468