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From Transparent Cranial Windows to Multifunctional Smart Cranial Platforms.
- Source :
- Electronics (2079-9292); Aug2022, Vol. 11 Issue 16, p2559-N.PAG, 16p
- Publication Year :
- 2022
-
Abstract
- In this paper, we briefly reviewed the development of cranial windows and their functions in brain sciences. We demonstrated that a 3D-printed titanium frame coated with a polydimethylsiloxane (PDMS) film could serve as an excellent transparent cranial window for long-period, in vivo optical experiments in mice and rats, and the devices also allowed multiple injections through the elastic PDMS window, without leaking. Our large-area honeycomb structured Ti-PDMS samples had a relative transparent area ratio of over 90% but a mechanical strength close to that of a human skull, showing a promising potential for applications in large animals as multifunctional cranial windows. We also suggested that more functional modules could be integrated in the large-area Ti-PDMS cranial device, thus turning it into a novel wearable smart platform for wireless data communication, electro-probing and brain stimulation, optical imaging, transcranial injection, and so on, for both fundamental research on neuroscience and clinical practices dealing with brain damage and disease. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 20799292
- Volume :
- 11
- Issue :
- 16
- Database :
- Complementary Index
- Journal :
- Electronics (2079-9292)
- Publication Type :
- Academic Journal
- Accession number :
- 158805450
- Full Text :
- https://doi.org/10.3390/electronics11162559