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A Key Protein Recognition Algorithm Based on High-order Complex Protein Network.
- Source :
- International Journal Bioautomation; 2022, Vol. 26 Issue 2, p193-208, 16p
- Publication Year :
- 2022
-
Abstract
- Although the existing protein recognition methods have improved the recognition accuracy of key proteins to a certain extent, they have ignored the biological features of the proteins. In view of this shortcoming, this paper constructed a high-order dynamic complex protein network for key protein recognition. At first, this paper presented a method for feature selection and candidate set evaluation of complex protein network; a weighted network was constructed based on the obtained topological features of the complex protein network and the semantic similarity of protein gene ontology annotations. Then, this paper proposed an algorithm for recognizing key proteins in high-order dynamic protein network based on a Fruit fly optimization algorithm. At last, the effectiveness of the proposed model was verified by experimental results. [ABSTRACT FROM AUTHOR]
- Subjects :
- PROTEINS
ALGORITHMS
FEATURE selection
GENE ontology
MATHEMATICAL optimization
Subjects
Details
- Language :
- English
- ISSN :
- 13141902
- Volume :
- 26
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- International Journal Bioautomation
- Publication Type :
- Academic Journal
- Accession number :
- 158802533
- Full Text :
- https://doi.org/10.7546/ijba.2022.26.2.000873