Increased Heme Oxygenase 1 Expression upon a Primary Exposure to the Respiratory Syncytial Virus and a Secondary Mycobacterium bovis Infection.

Since BCG has been used as an infection model of TB [[49], [52]], here we used an intranasal administration of BCG after the clearance of the infection with hRSV in mice to elucidate if this viral infection promotes an immune response that favors a secondary BCG infection. Graph: Figure 2 Evaluation of infection parameters from primary infection with a human respiratory syncytial virus (hRSV) and 11 days post-infection with Bacillus Calmette-Guerin (BCG). Supplementary Materials The following are available online at https://www.mdpi.com/article/10.3390/antiox11081453/s1, Figure S1: Gating strategy for identifying pulmonary cells found either in bronchoalveolar lavage (BAL) or in lung homogenates; Figure S2: Evaluation of infection parameters from primary infection with human respiratory syncytial virus (hRSV) and 21 days post-infection (dpi) with Bacillus Calmette-Guerin (BCG). Keywords: RSV; mycobacteria; HO-1; tuberculosis; susceptibility EN RSV mycobacteria HO-1 tuberculosis susceptibility N.PAG N.PAG 19 08/29/22 20220801 NES 220801 1. Graph: Figure 4 Determination of the relative expression of immunomodulatory molecules and cytokines in infection with Bacillus Calmette-Guerin (BCG) at 10 days post-human respiratory syncytial virus (hRSV)-infection. [Extracted from the article]