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Spontaneous regression of advanced-stage oropharyngeal squamous cell carcinoma.
- Source :
- Journal of Laryngology & Otology; Sep2022, Vol. 136 Issue 9, p882-884, 3p
- Publication Year :
- 2022
-
Abstract
- Background: Spontaneous regression is defined as the partial or complete disappearance of a malignant tumour proven by microscopic examination in the absence of any substantial treatment. This paper presents the case of an older woman whose advanced-stage tonsillar squamous cell carcinoma was noted to have spontaneously regressed at seven months. Case report: A 66-year-old woman presented with a 4-month history of dysphagia and odynophagia in September 2020. An exophytic tumour was seen on the right tonsil; this was diagnosed radiologically and histologically as a squamous cell carcinoma of the tonsils, with tumour–node–metastasis staging of T<subscript>4a</subscript>N<subscript>0</subscript>M<subscript>0</subscript>. The patient received best supportive care. Seven months later, the oropharyngeal lesion had disappeared, with no treatment. Subsequent computed tomography imaging showed radiological resolution of the previously noted right-sided oropharyngeal lesion. Conclusion: Several mechanisms of spontaneous regression are discussed. Further studies should review this case in conjunction with other reports of spontaneous tumour regressions, to elucidate underlying mechanisms. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00222151
- Volume :
- 136
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- Journal of Laryngology & Otology
- Publication Type :
- Academic Journal
- Accession number :
- 158510353
- Full Text :
- https://doi.org/10.1017/S0022215121002899