The minimal active domain of human salivary histatin 1 is efficacious in promoting acute skin wound healing.

In our latest in-vivo study, Hst1 not only promotes angiogenesis, re-epithelialization and collagen production, but also suppresses inflammation, thereby significantly accelerating acute skin wound healing in mice [[2]]. Keywords: Histatin 1; Minimal active domain; Acute skin wound; Inflammatory response; Oxidative stress EN Histatin 1 Minimal active domain Acute skin wound Inflammatory response Oxidative stress 1 4 4 08/09/22 20220716 NES 220716 Xiao-Xuan Lei, Liu Hang-Hang Cheng and Hai-Yan Lin have contributed equally to this work Dear Editor, The skin barrier can be impaired by acute skin wounds, which may lead to a series of complications. [Extracted from the article]