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Addressing barriers in comprehensiveness, accessibility, reusability, interoperability and reproducibility of computational models in systems biology.

Authors :
Niarakis, Anna
Waltemath, Dagmar
Glazier, James
Schreiber, Falk
Keating, Sarah M
Nickerson, David
Chaouiya, Claudine
Siegel, Anne
Noël, Vincent
Hermjakob, Henning
Helikar, Tomáš
Soliman, Sylvain
Calzone, Laurence
Source :
Briefings in Bioinformatics; Jul2022, Vol. 23 Issue 4, p1-11, 11p
Publication Year :
2022

Abstract

Computational models are often employed in systems biology to study the dynamic behaviours of complex systems. With the rise in the number of computational models, finding ways to improve the reusability of these models and their ability to reproduce virtual experiments becomes critical. Correct and effective model annotation in community-supported and standardised formats is necessary for this improvement. Here, we present recent efforts toward a common framework for annotated, accessible, reproducible and interoperable computational models in biology, and discuss key challenges of the field. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14675463
Volume :
23
Issue :
4
Database :
Complementary Index
Journal :
Briefings in Bioinformatics
Publication Type :
Academic Journal
Accession number :
158178066
Full Text :
https://doi.org/10.1093/bib/bbac212