42. FUNCTIONAL AND STRUCTURAL MRI ABNORMALITIES AND AUDITORY HALLUCINATIONS IN PSYCHOSIS.

Auditory hallucinations (AH) remain one of the most common and most debilitating symptoms in psychosis. Recent MRI-derived functional and structural measures have begun to elucidate the underlying pathology and pathophysiology related to AH. This session will describe recent advances in understanding the alterations in brain areas and brain dynamics that contribute to AH, including basal blood perfusion measures (Stegmayer), patterns of resting functional connectivity (Shinn), and white matter diffusion measures of abnormal structural connectivity (Kubicki, Salisbury). These data begin to reveal "hubs" and distributed circuits related to AH at the systems-level, and may provide insight into pathophysiology for targeted interventions, including non-invasive brain stimulation. [ABSTRACT FROM AUTHOR]