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A patient with hereditary transthyretin amyloidosis involving multiple cranial nerves due to a rare p.(Phe84Ser) variant.

Authors :
Xian-rang Yan
Ming-fan Hong
Zhi-hua Zhou
Ai-qun Liu
Zhong-xing Peng
Wei-feng Wu
Cheng Jing
Jia-xiu Lin
Ying Long
Qing-yun Yu
Source :
Translational Neuroscience; Jan2022, Vol. 13 Issue 1, p116-119, 4p
Publication Year :
2022

Abstract

We report a 30-year-old man involving gastrointestinal symptoms, vitreous opacity, and multiple cranial neuropathies. Transthyretin-related hereditary amyloidosis genetic testing revealed a rare c.251T > C variant p.(Phe84Ser). Only four cases with this variant have been reported before. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20813856
Volume :
13
Issue :
1
Database :
Complementary Index
Journal :
Translational Neuroscience
Publication Type :
Academic Journal
Accession number :
158008823
Full Text :
https://doi.org/10.1515/tnsci-2022-0219