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Whole-brain vascular reactivity measured by fMRI using hyperventilation and breath-holding tasks: efficacy of 3D prospective acquisition correction (3D-PACE) for head motion.
Whole-brain vascular reactivity measured by fMRI using hyperventilation and breath-holding tasks: efficacy of 3D prospective acquisition correction (3D-PACE) for head motion.
- Source :
- European Radiology; Aug2004, Vol. 14 Issue 8, p1484-1488, 5p
- Publication Year :
- 2004
-
Abstract
- Functional MR imaging (fMRI) study using hyperventilation and breath-holding task has been reported to be one of the non-invasive methods to examine whole-brain vascular reactivity. The purpose of this study was to evaluate the efficacy of a method for 3D prospective detection and correction of head motion (3D-PACE) in a study of whole-brain vascular reactivity using hyperventilation and breath-holding tasks. Eight healthy volunteers were scanned using an fMRI protocol of hyperventilation and breath-holding task blocks at 3 T in separate runs with and without 3D-PACE. In two subjects, two more runs with and without 3D-PACE were repeated. The mean total number of activated voxels +/- standard deviation was 26,405.3+/-1,822.2 in the run with 3D-PACE and 17,329.9+/-2,766.3 in the run without 3D-PACE ( P<0.05), although there is some intersubject variation regarding the effect of 3D-PACE. In the two subjects whose performed two more runs, the number of activated voxels were smaller in the run without 3D-PACE than even in the run with 3D-PACE performed later. We conclude that 3D-PACE is beneficial for fMRI studies of whole-brain vascular reactivity induced by hyperventilation and breath-holding. [ABSTRACT FROM AUTHOR]
- Subjects :
- BRAIN
MAGNETIC resonance imaging
DIAGNOSTIC imaging
CENTRAL nervous system
BRAIN anatomy
CEREBRAL circulation
COMPARATIVE studies
HYPERVENTILATION
RESEARCH methodology
MEDICAL cooperation
REFERENCE values
RESEARCH
RESEARCH evaluation
RESPIRATION
THREE-dimensional imaging
EVALUATION research
BODY movement
Subjects
Details
- Language :
- English
- ISSN :
- 09387994
- Volume :
- 14
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- European Radiology
- Publication Type :
- Academic Journal
- Accession number :
- 15781214
- Full Text :
- https://doi.org/10.1007/s00330-004-2342-0