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Whole-brain vascular reactivity measured by fMRI using hyperventilation and breath-holding tasks: efficacy of 3D prospective acquisition correction (3D-PACE) for head motion.

Whole-brain vascular reactivity measured by fMRI using hyperventilation and breath-holding tasks: efficacy of 3D prospective acquisition correction (3D-PACE) for head motion.

Authors :
Naganawa, Shinji
Koshikawa, Tokiko
Fukatsu, Hiroshi
Ishigaki, Takeo
Maruyama, Katsuya
Takizawa, Osamu
Source :
European Radiology; Aug2004, Vol. 14 Issue 8, p1484-1488, 5p
Publication Year :
2004

Abstract

Functional MR imaging (fMRI) study using hyperventilation and breath-holding task has been reported to be one of the non-invasive methods to examine whole-brain vascular reactivity. The purpose of this study was to evaluate the efficacy of a method for 3D prospective detection and correction of head motion (3D-PACE) in a study of whole-brain vascular reactivity using hyperventilation and breath-holding tasks. Eight healthy volunteers were scanned using an fMRI protocol of hyperventilation and breath-holding task blocks at 3 T in separate runs with and without 3D-PACE. In two subjects, two more runs with and without 3D-PACE were repeated. The mean total number of activated voxels +/- standard deviation was 26,405.3+/-1,822.2 in the run with 3D-PACE and 17,329.9+/-2,766.3 in the run without 3D-PACE ( P<0.05), although there is some intersubject variation regarding the effect of 3D-PACE. In the two subjects whose performed two more runs, the number of activated voxels were smaller in the run without 3D-PACE than even in the run with 3D-PACE performed later. We conclude that 3D-PACE is beneficial for fMRI studies of whole-brain vascular reactivity induced by hyperventilation and breath-holding. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09387994
Volume :
14
Issue :
8
Database :
Complementary Index
Journal :
European Radiology
Publication Type :
Academic Journal
Accession number :
15781214
Full Text :
https://doi.org/10.1007/s00330-004-2342-0