Clinical utility of botulinum toxin type A local injection therapy for head and forehead hyperhidrosis.

Head and forehead hyperhidrosis (HFH) is a disease that causes a large amount of sweating from the head region, and it significantly reduces patients' quality of life. Only a few reports have shown the effectiveness of botulinum toxin type A (BTX‐A) local injection therapy (BTX‐A therapy) for HFH. To clarify the benefits of BTX‐A for HFH, BTX‐A therapy was performed in 15 patients, and its efficacy was evaluated. The amount of sweating was measured by the ventilation capsule method and Minor's iodine‐starch test. Evaluation was also performed using the Hyperhidrosis Disease Severity Scale (HDSS) and the Dermatology Life Quality Index (DLQI). In most cases, a remarkable antiperspirant effect was observed from 2 weeks after the injection, and the effect lasted for approximately 30 weeks. HDSS and DLQI improved along with the decrease in sweating. Two patients (13.3%) complained of transient mild ptosis. There were no serious side‐effects. This study showed that BTX‐A therapy is a safe and effective treatment for HFH. [ABSTRACT FROM AUTHOR]