Back to Search
Start Over
Chemical constituents from the South China sea soft coral Sinularia humilis.
- Source :
- Natural Product Research; Jul2022, Vol. 36 Issue 13, p3324-3330, 7p
- Publication Year :
- 2022
-
Abstract
- A new diterpenoid with an unusual capnosane skeleton, sinuhumilol A (1), alone with twelve known diverse compounds (2–13), were isolated from the South China Sea soft coral Sinularia humilis. Their structures and stereochemistry were elucidated by extensive spectroscopic analysis, quantum chemical calculations, and/or by the comparison of the spectroscopic data with those reported in the literature. In bioassay, compound 11 exhibited interesting specific cytotoxicity against the human colon adenocarcinoma cell line HT-29 with IC<subscript>50</subscript> value of 12.5 µM. [ABSTRACT FROM AUTHOR]
- Subjects :
- ALCYONACEA
CELL lines
STEREOCHEMISTRY
BIOLOGICAL assay
Subjects
Details
- Language :
- English
- ISSN :
- 14786419
- Volume :
- 36
- Issue :
- 13
- Database :
- Complementary Index
- Journal :
- Natural Product Research
- Publication Type :
- Academic Journal
- Accession number :
- 157772423
- Full Text :
- https://doi.org/10.1080/14786419.2020.1855645