Synthesis, crystal structures and antibacterial activities of copper and nickel complexes derived from 5-bromo-2-((3-methylaminopropylimino)methyl)phenol.

Three new copper(II) and nickel(II) complexes, [Cu₃L₂(μ₂-NO₃)₂(μ_1,1-N₃)₂] (1), [Cu₂L₂(μ_1,1-N₃)₂]_n (2) and [Ni₃L₂(MeOH)₂(μ₂-η¹:η¹-CH₃COO)₂(μ₂-η²:η⁰-CH₃COO)₂] (3), where L = 5-bromo-2-((3-methylaminopropylimino)methyl)phenolate, have been synthesized and characterized. The complexes were characterized by elemental analyses, IR, UV–Vis spectra, molar conductivity, and single crystal X-ray diffraction. X-Ray analysis indicates that the Cu ions in 1 are in square pyramidal and octahedral coordination, and the Cu ions in 2 and the Ni ions in 3 are in octahedral coordination. The molecules of the complexes are linked through hydrogen bonds and π···π interactions. The complexes were assayed for antibacterial activities against three Gram-positive bacterial strains (Bacillus subtilis, Staphylococcus aureus, and Streptococcus faecalis) and three Gram-negative bacterial strains (Escherichia coli, Pseudomonas aeruginosa, and Enterobacter cloacae) by the MTT method. [ABSTRACT FROM AUTHOR]