Disinfection Protocols During the COVID-19 Pandemic and Their Effects on Prosthetic Surfaces: A Systematic Review.

Purpose: To describe the possible adverse effects of sodium hypochlorite (NaOCl) solutions, highconcentration alcohol solutions, and povidone-iodine products indicated for disinfection of inanimate surfaces against human coronavirus of the severe acute respiratory syndrome (SARS-CoV) on prosthesis materials, including zirconia, lithium disilicate, and acrylic resin. Materials and Methods: A systematic literature research was conducted in the SCOPUS, PubMed/Medline, Web of Science, EMBASE, and Science Direct databases from January 2010 to February 2020 using a combination of the following MeSH/Emtree terms and keywords: "sodium hypochlorite"; "alcohol"; "ethanol"; "povidone-iodine"; "dental ceramic"; "zirconia"; "lithium disilicate"; and "acrylic resin". Results: A total of 538 studies were identified in the search during initial screening, 44 were subject to full-text evaluation, and 24 fulfilled the inclusion criteria. Seven articles on zirconia and lithium disilicate investigated the effect of NaOCl (0.5% and 1%), 96% isopropanol, and 80% ethanol on bond strength after saliva contamination. The remaining articles evaluated color alteration, surface roughness modifications, decrease in flexural strength, and bond strength of all cleaning agents on acrylic resin. Conclusion: NaOCl solution (1%) for 1 minute is recommended to reduce SARSCoV infectivity and to minimize the risk of cross-contamination through prosthetic materials. An increase in surface roughness and color alteration on acrylic resin were recorded using 1% NaOCl, but without any clinical significance. A decrease in bonding strength was determined after using 1% NaOCl, 96% isopropanol, or 80% ethanol solutions on lithium disilicate. Silanization before the try-in procedure and the application of a second layer of silane after cleaning methods are recommended to improve the bond strength. [ABSTRACT FROM AUTHOR]