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Coenzyme Q10 supplementation for the treatment of statin-associated muscle symptoms.
- Source :
- Future Cardiology; Jun2022, Vol. 18 Issue 6, p461-470, 10p
- Publication Year :
- 2022
-
Abstract
- Aim: To determine the association of coenzyme Q10 (CoQ10) use with the resolution of statin-associated muscle symptoms (SAMS). Patients & methods: Retrospective analysis of a large, multicenter survey study of SAMS (total n = 511; n = 64 CoQ10 users). Univariate and multivariate logistic regression models assessed the association between CoQ10 use and the resolution of SAMS. Results: The frequency of SAMS resolution was similar between CoQ10 users and non-users (25% vs 31%, respectively; unadjusted odds ratio [OR]: 0.75 [95% CI: 0.41-1.38]; p = 0.357). Similarly, CoQ10 use was not significantly associated with the resolution of SAMS in multivariable models adjusted for SAMS risk factors (OR: 0.84 [95% CI: 0.45-1.55]; p = 0.568) or adjusted for significant differences among CoQ10 users and non-users (OR: 0.82 [95% CI: 0.45-1.51]; p = 0.522). Conclusion: CoQ10 was not significantly associated with the resolution of SAMS. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14796678
- Volume :
- 18
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Future Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 157277232
- Full Text :
- https://doi.org/10.2217/fca-2021-0106