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Assessing the Impact of Continuous Vaccination and Voluntary Isolation on the Dynamics of COVID-19: A Mathematical Optimal Control of SEIR Epidemic Model.
- Source :
- Computational Intelligence & Neuroscience; 6/2/2022, p1-13, 13p
- Publication Year :
- 2022
-
Abstract
- In order to study the impact of continuous vaccination and voluntary isolation for the COVID-19, a susceptible-exposed-infected-recovered-quarantine-vaccines (SEIR-QV) model is proposed. A basic regeneration number R 0 is defined to determine the extinction or persistence of the disease. We numerically analyze the impact of key parameters based on actual parameters of COVID-19, such as the vaccination rate, population importation rate, and natural (or causal) mortality transmission rate on the dynamics of disease transmission. Then we obtain sensitivity indices of some parameters on R 0 by sensitivity analysis. Finally, the stability of the system and the effectiveness of the optimal control strategy are verified by numerical simulation. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 16875265
- Database :
- Complementary Index
- Journal :
- Computational Intelligence & Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 157216546
- Full Text :
- https://doi.org/10.1155/2022/3309420