Sarcopenic Obesity with Normal Body Size May Have Higher Insulin Resistance in Elderly Patients with Type 2 Diabetes Mellitus.

Theoretically, because skeletal muscle is an important organ of insulin-mediated glucose metabolism,[13],[14] sarcopenia might exacerbate obesity-associated insulin resistance. Moreover body fat has better predictive validity on the development of the metabolic syndrome and cardiovascular disease risk than BMI.[46],[47] With aging T2DM patients are prone to have decreased skeletal muscle mass and increased body fat mass. Keywords: sarcopenic obesity; type 2 diabetes mellitus; elderly; insulin resistance; body composition EN sarcopenic obesity type 2 diabetes mellitus elderly insulin resistance body composition 1197 1206 10 05/11/22 20220401 NES 220401 Introduction The two greatest global health concerns are the aging of the population and widespread obesity, each of which has important effects on body composition. [Extracted from the article]