INTERMITTENT TETRACOSACTRIN-DEPOT THERAPY IN DERMATOLOGY.

Experience with tetracosactrin-depot therapy in 10 patients with dermatological disorders is described. The clinical response was considered good in 7 patients, poor in the remaining 3. Plasma cortisol levels remained elevated 24 to 48 hr, following injection but there were considerable differences between patients in both the magnitude and duration of response. Melanoderma and other side effects were troublesome when the total weekly dose exceeded 1 mg. Smaller dosages gave satisfactory response without significant accompanying side effects. [ABSTRACT FROM AUTHOR]