Editorial: Cellular Senescence and Cellular Communications Within Tissue Microenvironments During Aging.

These works uncovered a relatively comprehensive understanding of aging, and provided future perspectives for research on aging and aging interventions. Almost every cell in the body goes through the process of senescence, and the contribution of senescent cells to the body's unavoidable aging (we coined this "senescaging") cannot be ignored. Keywords: cellular senescence; aging; microenvironments; cellular communications; senescaging EN cellular senescence aging microenvironments cellular communications senescaging 1 3 3 04/14/22 20220411 NES 220411 Aging is expressed as a deterioration and frailty of various tissues, accompanied by dysregulation of the pathways essential for homeostasis, resilience, and maintenance ([1]; [6]; [7]). In recent years, many novel single-cell examination strategies have been constructed such as single-cell mass spectrometry ([13]), single-cell immunometabolic profiling ([2]), and single-cell-based immune cell research ([12]), allowing further exploration in the field of aging. [Extracted from the article]