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Solution processed low power organic field-effect transistor bio-chemical sensor of high transconductance efficiency.

Authors :
Tang, Wei
Fu, Ying
Huang, Yukun
Li, Yuanzhe
Song, Yawen
Xi, Xin
Yu, Yude
Su, Yuezeng
Yan, Feng
Guo, Xiaojun
Source :
NPJ Flexible Electronics; 3/18/2022, Vol. 6 Issue 1, p1-8, 8p
Publication Year :
2022

Abstract

Developing organic field-effect transistor (OFET) biosensors for customizable detection of biomarkers for many diseases would provide a low-cost and convenient tool for both biological studies and clinical diagnosis. In this work, design principles of the OFET transducer for biosensors were derived to relate the signal-to-noise ratio (SNR) to the device-performance parameters. Steep subthreshold swing (SS), proper threshold voltage (V<subscript>th</subscript>), good-enough bias-stress stability, and mechanical durability are shown to be the key prerequisites for realizing OFET bio-sensors of high transconductance efficiency (g<subscript>m</subscript>/I<subscript>D</subscript>) for large SNR. Combining a low trap-density channel and a high-k/low-k gate dielectric layer, low-temperature (<100 °C) solution-processed flexible OFETs can meet the performance requirements to maximize the g<subscript>m</subscript>/I<subscript>D</subscript>. An extended gate-structure OFET biosensor was further implemented for label-free detection of miR-21, achieving a detection limit below 10 pM with high selectivity at a low operation voltage (<1 V). [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23974621
Volume :
6
Issue :
1
Database :
Complementary Index
Journal :
NPJ Flexible Electronics
Publication Type :
Academic Journal
Accession number :
155873333
Full Text :
https://doi.org/10.1038/s41528-022-00149-9