Diclofenac‐induced adverse drug reactions and hyperbilirubinemia caused by a variant gene.

Diclofenac-induced adverse drug reactions and hyperbilirubinemia caused by a variant gene In addition, GI bleeding exacerbates bilirubin metabolism by supplying excess unconjugated bilirubin to the liver. A 76 years old man with a history of hyperbilirubinemia associated with diclofenac use was referred to our laboratory for genetic study. [Extracted from the article]