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Evaluation of Cheek Edema in an Infant Reveals Langerhans Cell Histiocytosis.

Authors :
Asimakopoulos, Asimakis D.
Panosetti, Eugene
Papoudou-Bai, Alexandra
Sioka, Chrissa
Source :
Ethiopian Journal of Health Sciences; Jan2022, Vol. 32 Issue 1, p217-220, 4p
Publication Year :
2022

Abstract

BACKGRAOUND: Langerhans cell histiocytosis is a rare hematological disorder. Skin rash is the typical early feature, and bony involvement is the second most common presentation. METHODS: We present a case of a 5-month-old female infant with left hemifacial swelling, initially treated for infection with antibiotics. However, due to persistence of swelling and new onset fever, further evaluation with ultrasonography, CT scan, FDG PET/CT and eventually biopsy was performed. RESULTS: Imaging methods revealed mandibular osteolysis indicative of either osteomyelitis or histiocytosis X. Tissue biopsy was diagnostic for Langerhans cell histiocytosis. CONCLUSION: Langerhans cell histiocytosis may present in infancy with a variety of symptoms, included an isolated bony lesion. Langerhans cell histiocytosis, despite its rarity, should be included in the differentiated diagnosis, when bone osteolysis is found. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10291857
Volume :
32
Issue :
1
Database :
Complementary Index
Journal :
Ethiopian Journal of Health Sciences
Publication Type :
Academic Journal
Accession number :
155736964
Full Text :
https://doi.org/10.4314/ejhs.v32i1.24