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Risk prediction model for deep surgical site infection (DSSI) following open reduction and internal fixation of displaced intra‐articular calcaneal fracture.
- Source :
- International Wound Journal; Mar2022, Vol. 19 Issue 3, p656-665, 10p
- Publication Year :
- 2022
-
Abstract
- Deep surgical site infection (DSSI) is a serious complication affecting the surgical outcome of displaced intra‐articular calcaneal fracture, and a risk prediction model based on the identifiable risk factors will provide great clinical value in prevention and prompt interventions. This study retrospectively identified patients operated for calcaneal fracture between January 2014 and December 2019, with a follow‐up ≥1 year. The data were extracted from electronic medical records, with regard to demographics, comorbidities, injury, surgery and laboratory biomarkers at admission. Univariate and multivariate logistics regression analyses were used to identify the independent factors for DSSI, thereby the risk prediction model was developed. Among 900 patients included, 2.7% developed a DSSI. The multivariate analyses identified five factors independently associated with DSSI, including current smoking (OR, 2.8; 95% confidence interval [CI], 1.3‐6.4; P =.021), BMI ≥ 26.4 kg/m2 (OR, 3.1; 95% CI, 1.6‐8.4; P =.003), ASA ≥II (OR, 1.3; 95% CI, 1.0‐5.1; P =.043), incision level of II (OR, 3.8; 95% CI, 1.3‐12.6; P =.018) and NLR ≥6.4 (OR, 3.2; 95% CI, 1.3‐7.5; P =.008). A score of 14 as the optimal cut‐off value was corresponding to sensitivity of 0.542 and specificity of 0.872 (area, 0.766; P <.001); ≥14 was associated with 8.1‐times increased risk of DSSI; a score of 7 was corresponding sensitivity of 100% and 10 corresponding to sensitivity of 0.875. The risk prediction model exhibited excellent performance in distinguishing the risk of DSSI and could be considered in practice for improvement of wound management, but its validity requires to be verified by better‐design studies. [ABSTRACT FROM AUTHOR]
- Subjects :
- STATISTICS
ACQUISITION of data methodology
CONFIDENCE intervals
MULTIVARIATE analysis
MULTIPLE regression analysis
OPEN reduction internal fixation
SURGERY
PATIENTS
RETROSPECTIVE studies
DISEASE incidence
RISK assessment
HEEL bone fractures
SURGICAL site infections
DESCRIPTIVE statistics
MEDICAL records
PREDICTION models
SENSITIVITY & specificity (Statistics)
ODDS ratio
SMOKING
RECEIVER operating characteristic curves
DISEASE risk factors
EVALUATION
Subjects
Details
- Language :
- English
- ISSN :
- 17424801
- Volume :
- 19
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- International Wound Journal
- Publication Type :
- Academic Journal
- Accession number :
- 155474038
- Full Text :
- https://doi.org/10.1111/iwj.13663