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The role of N-myristoylation in homeostasis of brassinosteroid signaling kinase 1.
- Source :
- Planta: An International Journal of Plant Biology; Apr2022, Vol. 255 Issue 4, p1-7, 7p
- Publication Year :
- 2022
-
Abstract
- Main conclusion: The N-myristoylation is required for BSK1 proper plasma membrane targeting and protein turnover. Brassinosteroid (BR) signaling kinase 1 (BSK1), with a myristoylation site at its N-terminus to anchor at plasma membrane (PM), is involved in BR-regulated plant growth and flg22-triggered immunity responses. However, little is known about the role of N-myristoylation in BSK1 protein homeostasis. Here, we revealed that N-myristoylation is critical to the PM targeting and protein stability of BSK1. The N-myristoylation-deficient mutant BSK1<superscript>G2A</superscript> mainly distributed in the cytoplasm and retained in the endoplasmic reticulum. We further found that the BSK1<superscript>G2A</superscript> proteins were unstable and degraded through ATG8e-labled autophagic pathway. This study provides a new insight into the regulation of plant protein homeostasis. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00320935
- Volume :
- 255
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Planta: An International Journal of Plant Biology
- Publication Type :
- Academic Journal
- Accession number :
- 155468426
- Full Text :
- https://doi.org/10.1007/s00425-022-03861-y