Cover Feature: Structure‐ and Interaction‐Based Design of Anti‐SARS‐CoV‐2 Aptamers (Chem. Eur. J. 12/2022).

Keywords: aptamers; fragment molecular orbitals method; molecular dynamics; SARS-CoV-2; SAXS EN aptamers fragment molecular orbitals method molecular dynamics SARS-CoV-2 SAXS 1 1 1 02/28/22 20220224 NES 220224 B Digital drug design reveals DNA aptamers binding SARS-CoV-2 b : A hybrid in silico et vitro approach, structure and interaction-based drug design, has been developed to create highly specific DNA aptamers for the receptor-binding domain of the SARS-CoV-2 spike protein. The structure and binding affinity of the aptamers were validated by small-angle X-ray scattering, flow cytometry, and fluorescence polarization. Cover Feature: Structure- and Interaction-Based Design of Anti-SARS-CoV-2 Aptamers (Chem. Eur. J. 12/2022). [Extracted from the article]