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Advances in laboratory detection methods and technology application of SARS‐CoV‐2.

Authors :
Zhang, Xiucai
Meng, Hanyan
Liu, Huihui
Ye, Qing
Source :
Journal of Medical Virology; Apr2022, Vol. 94 Issue 4, p1357-1365, 9p
Publication Year :
2022

Abstract

At present, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is raging worldwide, and the coronavirus disease 2019 outbreak caused by SARS‐CoV‐2 seriously threatens the life and health of all humankind. There is no specific medicine for novel coronavirus yet. So, laboratory diagnoses of novel coronavirus as soon as possible and isolation of the source of infection play a vital role in preventing and controlling the epidemic. Therefore, selecting appropriate detection techniques and methods is particularly important to improve the efficiency of disease diagnosis and treatment and to curb the outbreak of infectious diseases. In this paper, virus nucleic acid, protein, and serum immunology were reviewed to provide a reference for further developing virus detection technology to provide better prevention and treatment strategies and research ideas for clinicians and researchers. Highlights: Laboratory diagnoses of novel coronavirus play a vital role in the whole epidemic situation.Nucleic acid, protein and serum immunoassay of viruses are the main methods.RT‐PCR has become the gold standard for SARS‐CoV‐2 detection because of its high sensitivity and strong specificity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01466615
Volume :
94
Issue :
4
Database :
Complementary Index
Journal :
Journal of Medical Virology
Publication Type :
Academic Journal
Accession number :
155284038
Full Text :
https://doi.org/10.1002/jmv.27494