mRNA COVID‐19 vaccines in patients with chronic lymphocytic leukemia: A systematic review and meta‐analysis.

The impact of anti-COVID-19 vaccination was also assessed in CLL patients receiving therapy at the time of anti-COVID-19 vaccination ( I n i = 948 or 64.0%). According to our results, CLL treatment worsened the defective response to vaccination observed in CLL patients. Keywords: chronic lymphocytic leukemia; meta-analysis; mRNA SARS-CoV-2 vaccine; systematic review; treatment status EN chronic lymphocytic leukemia meta-analysis mRNA SARS-CoV-2 vaccine systematic review treatment status 264 267 4 02/09/22 20220301 NES 220301 ACKNOWLEDGMENTS None. Information on the type of therapy at the time of vaccination was available for 779 patients and allowed patients' stratification in four different therapeutic groups; Patients who had been given an anti-CD20 monoclonal antibody at any time before vaccination ( I n i = 254). [Extracted from the article]