Association between molecular markers of COVID‐19 and Alzheimer's disease.

Although the understanding of the etiology and pathogenesis of AD has been expanded in the last years, the potential association between COVID-19 and AD remains unclear.3 Importantly, some pathomechanisms related to AD are shared with COVID-19. In line with this, SARS-CoV-2 may activate glial cells, thus potentially triggering chronic neuroinflammation and neurodegeneration.3 Of note, the inflammatory response may lead to the neuronal death observed in postmortem samples of patients with COVID-19,4 as well as SARS-CoV-2 neuroinvasion may trigger neuropathological changes.5 Alzheimer's disease (AD) is the most common age-related neurodegenerative disease. Keywords: Infection; Inflammation; Immune responses; SARS coronavirus; Virus classification EN Infection Inflammation Immune responses SARS coronavirus Virus classification 833 835 3 01/21/22 20220301 NES 220301 The COVID-19 pandemic has represented an exceptional health challenge as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has acute and chronic consequences. [Extracted from the article]