Back to Search
Start Over
Season-of-birth phenomenon in health and longevity: epidemiologic evidence and mechanistic considerations.
- Source :
- Journal of Developmental Origins of Health & Disease; Dec2021, Vol. 12 Issue 6, p849-858, 10p
- Publication Year :
- 2021
-
Abstract
- In many human populations, especially those living in regions with pronounced climatic differences between seasons, the most sensitive (prenatal and neonatal) developmental stages occur in contrasting conditions depending on the season of conception. The difference in prenatal and postnatal environments may be a factor significantly affecting human development and risk for later life chronic diseases. Factors potentially contributing to this kind of developmental programming include nutrition, outdoor temperature, infectious exposures, duration of sunlight, vitamin D synthesis, etc. Month of birth is commonly used as a proxy for exposures which vary seasonally around the perinatal period. Season-of-birth patterns have been identified for many chronic health outcomes. In this review, the research evidence for the seasonality of birth in adult-life disorders is provided and potential mechanisms underlying the phenomenon of early life seasonal programming of chronic disease and longevity are discussed. [ABSTRACT FROM AUTHOR]
- Subjects :
- SEASON of birth
LONGEVITY
FETAL development
CHRONIC diseases
PERINATAL period
Subjects
Details
- Language :
- English
- ISSN :
- 20401744
- Volume :
- 12
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Journal of Developmental Origins of Health & Disease
- Publication Type :
- Academic Journal
- Accession number :
- 154756882
- Full Text :
- https://doi.org/10.1017/S2040174420001221