Understanding basal cell adenocarcinoma of the head and neck: Population‐based study.

Background: Using a population‐based database, this study investigates the risk factors, epidemiology, and outcomes of basal cell adenocarcinoma (BCAC) of the head and neck. Methods: The Surveillance, Epidemiology, and End Results database was analyzed for all patients with BCAC of the head and neck from 1973 to 2015. Results: Three hundred and twenty‐two cases of BCAC of the head and neck were identified. Mean age of diagnosis was 64.1 years. 52.5% were male and 77.3% were white. The most common primary site was the parotid gland (71.7%). Most patients underwent surgery alone (51.9%). Five‐year disease‐specific survival (5Y‐DSS) was 95.6%, and 10Y‐DSS was 90.3%. Highest survival was seen with surgery alone followed by combined surgery and radiation (10Y‐DSS: 93.9% vs. 88.9%, p = 0.001). Age, primary site, T‐classification, grade, and treatment type significantly affected survival. Conclusions: BCAC of the head and neck presents most frequently in the parotid glands. Surgery alone is associated with highest survival. [ABSTRACT FROM AUTHOR]