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Mechanisms of COVID-19-induced kidney injury and current pharmacotherapies.

Authors :
Faour, Wissam H.
Choaib, Ali
Issa, Elio
Choueiry, Francesca El
Shbaklo, Khodor
Alhajj, Maryline
Sawaya, Ramy Touma
Harhous, Zeina
Alefishat, Eman
Nader, Moni
Source :
Inflammation Research; Jan2022, Vol. 71 Issue 1, p39-56, 18p
Publication Year :
2022

Abstract

The COVID-19 pandemic created a worldwide debilitating health crisis with the entire humanity suffering from the deleterious effects associated with the high infectivity and mortality rates. While significant evidence is currently available online and targets various aspects of the disease, both inflammatory and noninflammatory kidney manifestations secondary to COVID-19 infection are still largely underrepresented. In this review, we summarized current knowledge about COVID-19-related kidney manifestations, their pathologic mechanisms as well as various pharmacotherapies used to treat patients with COVID-19. We also shed light on the effect of these medications on kidney functions that can further enhance renal damage secondary to the illness. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10233830
Volume :
71
Issue :
1
Database :
Complementary Index
Journal :
Inflammation Research
Publication Type :
Academic Journal
Accession number :
154708556
Full Text :
https://doi.org/10.1007/s00011-021-01520-8