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ZFTA‐YAP1 fusion‐positive ependymoma can occur in the spinal cord: Letter to the editor.
- Source :
- Brain Pathology; Jan2022, Vol. 32 Issue 1, p1-5, 5p
- Publication Year :
- 2022
-
Abstract
- MPE, myxopapillary ependymoma; PFA-EPN, posterior fossa group A ependymoma; PFB-EPN, posterior fossa group B ependymoma; PF-SUBEPN, posterior fossa-subependymoma; PN, ependymoma; SP-EPN, spinal-ependymoma; SP-SUBEPN, spinal subependymoma; ST-EPN-ZFTA, supratentorial-ependymoma ZFTA fusion-positive; ST-SUBEPN, supratentorial subependymoma; YAP1-EPN, ST-ependymoma YAP1-positive gl Our case might be the first case of SP-EPN harboring a I ZFTA-YAP1 i fusion. ZFTA-YAP1 fusion-positive ependymoma can occur in the spinal cord: Letter to the editor Although I ZFTA i fusion-positive EPN occurs mainly in the supratentorial region, one I ZFTA i - I RELA i fusion-positive EPN in the cerebellum and one I ZFTA i - I MAML2 i fusion-positive EPN in the cervical junction have been reported [9]. Unsupervised t-SNE analysis with an overlay on the known ependymal tumor clusters revealed that our case belonged to ST-EPN- I RELA i (now the same as I ZFTA i -fusion-positive ST-EPN), not SP-EPN. [Extracted from the article]
- Subjects :
- SPINAL cord
EPENDYMOMA
CENTRAL nervous system tumors
Subjects
Details
- Language :
- English
- ISSN :
- 10156305
- Volume :
- 32
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Brain Pathology
- Publication Type :
- Academic Journal
- Accession number :
- 154358418
- Full Text :
- https://doi.org/10.1111/bpa.13020