A scientific journey from discovery to validation of efficacy in cancer patients: HAMLET and alpha1-oleate.

Authors :: Ho, James C.S.
Ambite, Ines
Mok, K. H.
Babjuk, Marek
Svanborg, Catharina
Source :: Molecular & Cellular Oncology; 2021, Vol. 8 Issue 5, p1-3, 3p
Publication Year :: 2021
Abstract: The protein-lipid complex alpha1-oleate, derived from HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells), is identified as a molecular entity with significant therapeutic potential. Structural characterization of the complex and results of a successful placebo-controlled clinical trial are presented. [ABSTRACT FROM AUTHOR]

Subjects :: CANCER patients
PROTEINS
TUMORS
PLACEBOS
PEPTIDES
BLADDER cancer

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