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The relationships of lifetime physical activity and diet with salivary cell telomere length in current ultra-endurance exercisers.
- Source :
- Nutrition & Healthy Aging; 2021, Vol. 6 Issue 3, p179-189, 11p
- Publication Year :
- 2021
-
Abstract
- BACKGROUND: Physical activity and a healthy diet may delay the aging process and ultra-endurance exercise is an extreme form of physical activity. Telomeres are protective DNA sequences located at the ends of eukaryotic chromosomes which shorten as we age. OBJECTIVE: The aim of this study was to investigate the relationships of lifetime physical activity and diet with salivary cell telomere length in current ultra-endurance exercisers (n = 49; % female = 37, age range 26–74 years). METHODS: Physical activity and dietary intake were measured using the Lifetime Physical Activity and Diet Questionnaire (LPADQ) and salivary cell telomere length was measured using quantitative polymerase chain reaction. RESULTS: In this group of current ultra-endurance exercisers there was no relationship between lifetime physical activity or diet (according to food category scores) and telomere length. In contrast to the expected age-related decrease in telomere length, there was no relationship between age and telomere length (95% confidence interval [CI]: –38.86, 14.54, p = 0.359) in this group of current ultra-endurance exercisers. CONCLUSIONS: The relationships of lifetime physical activity and diet with telomere length remain uncertain. It is possible that lifetime physical activity (including ultra-endurance exercise) and lifetime diet may independently, or in combination, contribute to a decrease in the rate of age-related telomere shortening in current ultra-endurance exercisers. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 24519480
- Volume :
- 6
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Nutrition & Healthy Aging
- Publication Type :
- Academic Journal
- Accession number :
- 153712984
- Full Text :
- https://doi.org/10.3233/NHA-200090