Regional Variation in Fracture-Associated Prescription Drug Use and Hip Fractures in Long-Term Care: an Observational Study.

Logistic regression modelled hip fracture risk associated with HRR-level intensity of multiple drug receipt adjusted for age, sex, and race/ethnicity using SAS software, version 9.4. Question: How much regional variation exists in the intensity of fracture-associated drug use in the long-term care (LTC) setting, and how is this variation associated with fracture risk? Logistic regression demonstrated modest but significant hip fracture risk associated with HRR-level total drug use intensity, comparing HRRs in the highest versus lowest quintile (OR = 1.13, 95% CI 1.08-1.19, I p i < 0.001). [Extracted from the article]