Two‐step irradiance provides less pain with similar efficacy in photodynamic therapy on chinese patients with moderate to severe acne.

Two-step irradiance provides less pain with similar efficacy in photodynamic therapy on chinese patients with moderate to severe acne A retrospective review of pain control by a two-step irradiance schedule during topical ALA-photodynamic therapy of non-melanoma skin cancer. Two-step irradiance schedule (2-SIS) has been shown to significantly reduce pain during topical 5-aminolevulinic acid photodynamic therapy (ALA-PDT) on non-melanoma skin cancer (NMSC) and condyloma acuminatum (CA).1,2 Few studies focused on 2-SIS pain control during PDT for acne. [Extracted from the article]