The possibilities of pharmacological intervention in myopia.

This paper presents and discusses the current possibilities of pharmacological intervention in myopia. A review of the latest literature regarding the pharmacological treatment of myopia has been presented. The results of experimental research on the potential use of: atropine, oxyphenonium, pirenzepine, chlorpyrifos, apomorphine, reserpine, 6-hydroxy dopamine, dextromethorphan, MK-801, APV, bicuculline, SR95531, CACA, TPMPA, dextrophanol, levorphanol, D- and L-naloxane, L-NAME, formoguanamine, b-xyloside, the central and peripheral antagonist of VIP, basic fibroblast growth factor, a solution of the basic amino acid salts in the form of succinates, in the treatment of myopia have been described. The clinical use of pirenzepine, 7-methylxanthine, and atropine has been discussed. The obtained results of experimental and clinical studies give hope that a new effective pharmacological method of myopia treatment can be discovered soon. [ABSTRACT FROM AUTHOR]