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Sociodemographic and psychosocial predictors of longitudinal antiretroviral therapy (ART) adherence among first-time ART initiators in Cape Town, South Africa.
- Source :
- AIDS Care; Nov 2021, Vol. 33 Issue 11, p1394-1403, 10p, 3 Charts
- Publication Year :
- 2021
-
Abstract
- First-time antiretroviral therapy (ART) initiators may be more vulnerable to poor ART adherence because they may be coping with a new HIV diagnosis, facing logistical challenges to accessing and adhering to ART for the first time, and have not yet developed support networks or the skills to support long-term adherence. We recruited 324 participants in two HIV clinics near Cape Town, South Africa. Sociodemographic/psychosocial factors were measured at baseline and self-reported adherence at the 6 month follow-up. We conducted multivariable regression to determine which baseline factors were associated with 6-month adherence. A better patient-clinic relationship score (OR: 1.08 [95% CI: 1.05–1.11]) was associated with higher adherence. A drug use problem (0.51 [0.29–0.87]), higher social isolation (0.93 [0.87–0.99]), and greater number of years living with HIV before initiating ART (0.92 [0.86–1.00]) were associated with adherence levels below 90%. Patient-clinic relationships and social support are key psycho-social factors in early adherence behavior. Reducing drug use problems through targeted screening and early intervention may improve ART adherence. [ABSTRACT FROM AUTHOR]
- Subjects :
- CLINICAL drug trials
HIV infections
ANTI-HIV agents
SOCIAL support
SUBSTANCE abuse
CONFIDENCE intervals
SELF-evaluation
SOCIOECONOMIC factors
PATIENTS' attitudes
SOCIAL isolation
DESCRIPTIVE statistics
PATIENT compliance
LOGISTIC regression analysis
PATIENT-professional relations
ODDS ratio
PSYCHOLOGY of HIV-positive persons
Subjects
Details
- Language :
- English
- ISSN :
- 09540121
- Volume :
- 33
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- AIDS Care
- Publication Type :
- Academic Journal
- Accession number :
- 153295937
- Full Text :
- https://doi.org/10.1080/09540121.2020.1798336