Update on French recommendations for the treatment of uncomplicated Neisseria gonorrhoeae infections.

The article discusses the updated French recommendations for the treatment of uncomplicated Neisseria gonorrhoeae (NG) infections. The main therapeutic recommendation is now dual therapy with a single dose of intramuscular ceftriaxone (CRO) and a single dose of oral azithromycin (AZM). This is in response to the increasing antimicrobial resistance of NG and the risk of gonorrhea becoming untreatable. The article also highlights the poor track record of AZM against sexually transmitted infections and the resistance that has developed. The French Society of Dermatology and Venerology, the French Society of Infectious Diseases, and the National Reference Centre for Bacterial STI jointly recommend the use of CRO as a single-dose treatment for uncomplicated anogenital NG infections. For oropharyngeal infections, tailored therapy based on the resistance profile of NG isolates is recommended, with a dual therapy of CRO and AZM preferred for patients returning from the Asia Pacific region where CRO resistance is high. [Extracted from the article]