Transition of cutaneous into systemic lupus erythematosus following adenoviral vector‐based SARS‐CoV‐2 vaccination.

We report a case of subacute cutaneous lupus erythematosus (SCLE) that transitioned into systemic lupus erythematosus (SLE) following AdV-vaccination with AZD1222. These findings indicate a transition of SCLE into SLE, fulfilling the current SLE classification criteria.2 Under tapered glucocorticosteroid therapy with prednisolone 250 mg/day, the skin lesions and systemic symptoms significantly improved within 7 days. Transition of cutaneous into systemic lupus erythematosus following adenoviral vector-based SARS-CoV-2 vaccination. [Extracted from the article]