Risk stratification for children with a solitary functioning kidney.

The authors reflect on the risk stratification for children with only one functioning kidney and the possible risks faced by a solitary functioning kidney (SFK). Also cited are the hyperfiltration hypothesis stating that reduced number of nephrons could cause glomerular hyperfiltration which may result in hypertension, albuminuria, and glomerulosclerosis, and the risk factors like genetic, perinatal, and urinary tract abnormalities.