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Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothers.
- Source :
- Jornal de Pediatria; Sep/Oct2021, Vol. 97 Issue 5, p520-524, 5p
- Publication Year :
- 2021
-
Abstract
- Objective: To evaluate cardiac function and structural changes in children of diabetic mothers in the fetal and neonatal period using Doppler-echocardiographic data. Method: A prospective, descriptive observational study conducted in a private and tertiary care service for high-risk pregnant women. It included 48 children of mothers with gestational diabetes mellitus (GDM) considered clinically compensated during pregnancy, with a single fetus and absence of malformations. Myocardial thickness, shortening fraction, left ventricular (LVMPI) and right ventricular (RVMPI) myocardial performance index, and mitral and tricuspid valve E/A ratio were evaluated in 96 echocardiographic exams with Doppler. Results: The hypertrophic cardiomyopathy was 29% vs 6% p = 0.006 in the prenatal and postnatal periods respectively. The shortening fraction was 0% vs 6% p = 0.242 in the fetuses and newborns respectively. The myocardial performance index of the right ventricle was 12% vs 54% p = 0.001, and on the left ventricle 27% vs 60% p = 0.001 in the prenatal and postnatal periods respectively. The ratio of mitral valve E/A waves was 6% vs 50% p = 0.001 and the ratio of tricuspid valve E/A waves was 0% vs 27% p = 0.001 in the fetuses and newborns respectively. Conclusion: A decrease in the rate of myocardial hypertrophy and changes in cardiac function parameters were observed in the fetal and neonatal periods. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00217557
- Volume :
- 97
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Jornal de Pediatria
- Publication Type :
- Academic Journal
- Accession number :
- 152530119
- Full Text :
- https://doi.org/10.1016/j.jped.2020.10.003