Identification and Induction by β-naphthoflavone of CYP1A1 in Liver of the Neotropical Fish Pacu, Piaractus mesopotamicus(Characiformes: Characidae).

Authors :: Bastos, V. L. F. Cunha
Pinto, L. F. Ribeiro
Lima, L. M.
Bastos, J. Cunha
Source :: Bulletin of Environmental Contamination & Toxicology; Jan2004, Vol. 72 Issue 1, p13-20, 8p
Publication Year :: 2004
Abstract: The article describes the presence of cytochromes P450 in liver microsomes from pacu and its major specific deethylase activity, which was inducible by β-napthoflavone. Pacus of both sexes weighing around 400 gram were donated by the National Centre for Research on Tropical Fish of the Brazilian Environment and Renewable Natural Resources Institute. They were acclimated for three weeks in 500 liter tanks equipped with biologic filter and filled with aerated dechlorinated freshwater at 24 &degree;Celsius.

Full Text Access

Tools