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A red-emissive two-photon fluorescent probe for mitochondrial sodium ions in live tissue.
- Source :
- Chemical Communications; 9/14/2021, Vol. 57 Issue 71, p8929-8932, 4p
- Publication Year :
- 2021
-
Abstract
- A cyclocyanine (CC)-based organic small molecule two-photon (TP) fluorescent probe (CCNa1) was developed for mitochondrial sodium ion sensing. CCNa1 exhibits a low solvatochromic shift and strong TP fluorescence enhancement at 575 nm upon binding to Na<superscript>+</superscript> and is insensitive to other metal ions and to pH. CCNa1 demonstrated fast cell loading ability, biocompatibility, and sensitive response to mitochondrial Na<superscript>+</superscript> influx in live cells and mouse brain tissue. [ABSTRACT FROM AUTHOR]
- Subjects :
- SODIUM ions
FLUORESCENT probes
MITOCHONDRIA
SMALL molecules
METAL ions
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 57
- Issue :
- 71
- Database :
- Complementary Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 152271114
- Full Text :
- https://doi.org/10.1039/d1cc03617c