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A pendant droplet-based sensor for the detection of acetylcholinesterase and its inhibitors.

Authors :
Li, Benyou
Guo, Yongxian
Jiang, Yifei
Lin, Jin-Ming
Hu, Qiongzheng
Yu, Li
Source :
Chemical Communications; 9/14/2021, Vol. 57 Issue 71, p8909-8912, 4p
Publication Year :
2021

Abstract

In this work, a pendant droplet-based sensor is developed for the rapid and label-free detection of acetylcholinesterase (AChE) and its inhibitors. The detection limit of AChE reaches 0.17 mU mL<superscript>−1</superscript>. The pIC<subscript>50</subscript> values of AChE inhibitors such as neostigmine, rivastigmine and galantamine are determined to be 0.45 μM, 0.64 μM and 4.93 μM, respectively. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
57
Issue :
71
Database :
Complementary Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
152271107
Full Text :
https://doi.org/10.1039/d1cc03370k