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The demography and characteristics of SARS-CoV-2 seropositive residents and staff of nursing homes for older adults in the Community of Madrid: the SeroSOS study.
- Source :
- Age & Ageing; Jul2021, Vol. 50 Issue 4, p1038-1047, 10p, 1 Diagram, 4 Charts
- Publication Year :
- 2021
-
Abstract
- Background Nursing homes for older adults have concentrated large numbers of severe cases and deaths for coronavirus disease 2019 (COVID-19). Methods Point seroprevalence study of nursing homes to describe the demography and characteristic of severe acute respiratory syndrome by coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG)-positive residents and staff. Results Clinical information and blood samples were available for 9,332 residents (mean age 86.7 ± 8.1 years, 76.4% women) and 10,614 staff (mean age 45.6 ± 11.5, 86.2% women). Up to 84.4% of residents had frailty, 84.9% co-morbidity and 69.3% cognitive impairment; 65.2% of workers were health-aides. COVID-19 seroprevalence was 55.4% (95% confidence interval (CI), 54.4–56.4) for older adults and 31.5% (30.6–32.4) for staff. In multivariable analysis, frailty of residents was related with seropositivity (odds ratio (OR): 1.19, P  = 0.02). In the case of staff, age > 50 years (2.10, P  < 0.001), obesity (1.19, P  = 0.01), being a health-aide (1.94, P  < 0.001), working in a center with high seroprevalence in residents (3.49, P  < 0.001) and contact with external cases of COVID-19 (1.52, P  < 0.001) were factors associated with seropositivity. Past symptoms of COVID-19 were good predictors of seropositivity for residents (5.41, P  < 0.001) and staff (2.52, P  < 0.001). Conclusions Level of dependency influences risk of COVID-19 among residents. Individual and work factors, contacts outside the nursing home are associated with COVID-19 exposure in staff members. It is key to strengthen control measures to prevent the introduction of COVID-19 into care facilities from the community. [ABSTRACT FROM AUTHOR]
- Subjects :
- COGNITION disorders
RESEARCH
SEROPREVALENCE
OBESITY
COVID-19
IMMUNOGLOBULINS
FRAIL elderly
CONFIDENCE intervals
NURSING home patients
SICK people
MULTIVARIATE analysis
AGE distribution
MEDICAL personnel
COMMUNITIES
BLOOD collection
PSYCHOSOCIAL factors
DESCRIPTIVE statistics
VIRAL antibodies
ODDS ratio
NURSING home employees
COMORBIDITY
OLD age
Subjects
Details
- Language :
- English
- ISSN :
- 00020729
- Volume :
- 50
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Age & Ageing
- Publication Type :
- Academic Journal
- Accession number :
- 151354092
- Full Text :
- https://doi.org/10.1093/ageing/afab096