Survival outcomes in patients with parotid gland carcinoma treated with postoperative therapies using risk stratification.

Background: To evaluate the role of postoperative treatment in parotid gland carcinoma (PGC) based on risk stratification. Material and Methods: A total of 301 PGC patients were retrospectively analyzed using risk stratification. The Kaplan–Meier method and Cox analysis were performed to conduct survival analysis. Results: In the high‐risk group, those treated with postoperative radiotherapy (RT) had a better 5‐year disease‐free survival (DFS) than those treated with surgery alone. In the low‐risk group, both surgery + RT and surgery + chemotherapy (CT) significantly improved DFS when compared with surgery alone. Cox analysis showed that patients who underwent surgery + RT or surgery + CT had a lower risk of disease progression than those who underwent surgery alone in the low‐risk group. In the high‐risk group, patients who underwent surgery + RT had a lower risk of disease progression. Conclusions: Postoperative RT showed considerable benefit in improving disease control in patients with PGC, even in those without high‐risk factors. [ABSTRACT FROM AUTHOR]