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Highly Diastereoselective Hydrosilane‐Assisted Rhodium‐Catalyzed Spiro‐Type Cycloisomerization of Succinimide and Pyrazolone‐Based Functional 1,6‐Dienes.
- Source :
- Chemistry - An Asian Journal; 7/5/2021, Vol. 16 Issue 13, p1730-1734, 5p
- Publication Year :
- 2021
-
Abstract
- Organosilicon compounds are important reagents and synthetic intermediates that play a key role in the construction of new materials and complex products. Here we show a highly diastereoselective rhodium‐catalyzed cycloisomerization of 1,6‐dienes, in which the use of (EtO)3SiH accelerates the intramolecular cyclization reaction to afford a novel spiro‐fused succinimide and pyrazolone derivatives in moderate to excellent yields as a single diastereoisomer. The proposed mechanism involves an active Rh−H species from the hydrosilane that is the H‐donor in this spiro‐type cycloisomerization reaction. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 18614728
- Volume :
- 16
- Issue :
- 13
- Database :
- Complementary Index
- Journal :
- Chemistry - An Asian Journal
- Publication Type :
- Academic Journal
- Accession number :
- 151210403
- Full Text :
- https://doi.org/10.1002/asia.202100372