Synthesis of magnetic fluid based on local iron sand using natural surfactants and their potential as hyperthermia therapy.

Magnetic fluid based on local iron sand using virgin coconut oil (VCO) as a natural surfactant is a magnetic fluid that has good biocompatible properties. Fe₃O₄/VCO preparation was successfully synthesized using the coprecipitation method. The Fe₃O₄ nanoparticles obtained were characterized by using XRD and SEM. The XRD results showed a particle size was 11.28 nm. These results were well confirmed using SEM characterization, which showed that the particle size was 11.34 nm. FTIR characterization shows the bond -CH-(CH₂) with an asymmetric vibration model that experiences a shift in the peak vibration on the magnetic fluid sample, and it is a representation presence of oleic acid as one of the substances in the VCO surfactant. Furthermore, a new peak with the -COO- bond shows carboxylic acids as evidence of the combination of symmetrical bonding with surface molecular bonds. This indicates that the addition of VCO surfactants can reduce the agglomeration of magnetite nanoparticles. To determine the Specific Absorption Rate (SAR) value we used magneto-thermal characterization. From the analysis, SAR value of magnetic fluid indicates 1.659 and 2.021 W/g for the Fe₃O₄/VCO ratio of 1 : 3.5 and 1 : 4.5, respectively. From these results, the magnetic fluid of Fe₃O₄/VCO is a potential candidate as a material for hyperthermia therapy. [ABSTRACT FROM AUTHOR]