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Sex differences in continuous-flow ventricular assist device therapy for advanced heart failure.
- Source :
- General Thoracic & Cardiovascular Surgery; Jun2021, Vol. 69 Issue 6, p919-925, 7p
- Publication Year :
- 2021
-
Abstract
- Objective: The effect of patient sex in continuous-flow ventricular assist device (c-VAD) therapy has not been well described. We investigated sex-specific differences in clinical outcomes related to c-VAD therapy for Japanese patients. Methods: We retrospectively analyzed 153 patients, including 41 (27%) female patients who underwent c-VAD implantation over the last 13 years in our institution for a mean follow-up of 766 ± 446 days. Clinical outcomes were compared between male and female patients Results: There was no significant difference in mortality, cerebral vascular accidents, the severity of heart failure, or driveline infection in patients who underwent c-VAD implantation, regardless of sex. While male patients tended to have more bleeding at the time of surgery, female patients had significantly higher rates of non-surgical bleeding during subsequent c-VAD therapy, mainly from gynecological origins. Conclusions: Female patients treated with c-VAD had a significantly higher incidence of non-surgical bleeding events. Careful attention to gynecological complications and sex-specific care is required in female patients with c-VAD. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 18636705
- Volume :
- 69
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- General Thoracic & Cardiovascular Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 150363225
- Full Text :
- https://doi.org/10.1007/s11748-020-01538-5